Viruses: Mechanisms of Immune Evasion and Involvement in Periodontal Diseases – a Review Article
نویسندگان
چکیده
Periodontitis is a multilayered factors disease with diverse clinical features not precisely explained by the etiologic role of bacteria. Herpesviruses have been found in periodontally affected sites by PCR. Herpesviruses are known to exert immune regulation and thus, variations on inflammatory and immune responses attributed to them may reduce host resistance against subgingival colonization and multiplication of periodontal pathogens. More trials to evaluate whether the effects seen in observational studies are truly related to herpesviruses could bring a causative and conclusive proof for their specific effect in periodontal disease. UNITERMS: H e r p e s v i r i d a e / i m m u n o l o g y ; Cytomegalovirus; Herpesvirus 4, Human; Simplexvirus; Periodontitis/etiology. periojun2009 08-06-10.pmd 6/8/2010, 10:38 AM 43 R. Periodontia 19(2):38-44
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